How does alcohol affect the immune system?

Even a single night of heavy drinking can leave you more vulnerable to infections for up to 24 hours. This is because alcohol can disrupt the production of white blood cells, which are crucial for fighting off invaders. When we think about our immune system, we often picture a robust defense mechanism that keeps us healthy and resilient against infections.

how does alcohol affect the immune system

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In recent decades, medical research has increasingly focused on understanding the relationship between alcohol use and what is alcoholism immune function. Health professionals have observed that people who drink heavily often experience more frequent illnesses, and recovery from infections or injuries tends to be slower compared to those who either abstain or consume alcohol minimally. The biochemical mechanisms behind these observations involve direct and indirect effects, including alterations to immune cells, damage to organs that play a vital role in immunity, and disruption of protective barriers that help keep pathogens at bay. Alcohol also may reduce the ability of lymphocytes to proliferate and differentiate adequately after they have been activated by an antigen.

Scientific Studies on Alcohol and Immunity

  • Various types of Igs (e.g., IgA, IgG, IgM) are produced at different times during an infection or in response to a range of antigens that have specific roles in the adaptive immune response.
  • These results could support a role, via an anti-inflammatory mechanism, for moderate alcohol intake in cardiovascular disease (CVD) prevention.
  • The antibodies are distributed throughout the bloodstream and bind to the bacteria wherever they encounter them, aided by proteins of the complement system.

Simply put, the immune system is what protects our bodies from harmful substances, defends against infections and produces antibodies to help fight off any toxins, germs or viruses in the body (antigens). It’s important to maintain a healthy immune system to aid recovery when how does alcohol affect the immune system you’re unwell, lessening the intensity of symptoms and decreasing the risk of infections. T-cells and B-cells are critical for long-term immunity and vaccine response.

Alcohol’s Effects on the Body

how does alcohol affect the immune system

All of these effects enhance the susceptibility of chronic alcoholics to viral and bacterial infections and to sterile inflammation. As this review has indicated, alcohol exposure, and particularly chronic alcohol use, has profound effects on all aspects of the body’s immune responses, including both innate and adaptive immunity. These effects can impair the body’s defenses against a wide range of pathogens, including viruses and bacteria, as well as against damaged self and can affect tissues and organs throughout the body (see the figure).

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